Vi-CELL BLU Cell Viability Analyzer
The Vi-CELL BLU cell viability analyzer automates the Trypan Blue Dye Exclusion method for cell viability analysis. It now expedites processing by having the option to use a 24-position sample carousel or a 96-well plate for sample delivery.
Additional enhancements incorporated in the Vi-CELL BLU cell viability analyzer include:
- Fully automated sample preparation, analysis and post-run cleaning
- Sample volume: 200 µL, large sample capacity
- Processing time: 130 s per sample
- Log in samples on the fly
- Small laboratory footprint
- Flexible sample introduction – carousel or 96-well plate
- Reagent system
- Cell viability reported in percentage, concentration, and cell count
- Data integrity tools for 21 CFR Part 11 compliance, single sign-on with Active Directory
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Product Overview
Vi-CELL BLU Cell Viability Analyzer Features
Increased Productivity
- FAST mode
- 24-position carousel
- Supports 96-well plate sample introduction
- Customizable analysis parameters
Flexibility and Ease of Use
- Easy sample vial dispensing
- Easy load reagent pack
- Load on-the-go processing
- Cleanroom kit option
Reagent Pack
- RFID tracking of reagent part number, lot number, activities, and expiration date
- Easy load for automated sample prep
- Reagent pack complete with Trypan Blue dye, buffer, disinfectant and cleaning solutions
Data Integrity and Compliance
- Audit trail
- Error log files
- Electronic signature capability
- Secure user sign-on
- User level permissions
- Administrative configuration tools
- IQ/OQ
Vi-CELL BLU Insights and Resources
Key Features and Benefits
Discover the automation, accuracy, and data analysis capabilities that make the Vi-CELL BLU Cell Viability Analyzer a reliable solution for cell counting and viability testing.
Explore FeaturesFrom Data to Insights
Learn how the Vi-CELL BLU analyzer transforms cell count and viability measurements into meaningful insights that support informed decision-making.
Learn How It WorksCell Type Guidelines
Explore validated cell type settings and recommended configurations to help optimize performance across a range of cell-based applications.
View Cell Type Guidelines21 CFR Part 11 Compliance
Explore the Vi-CELL BLU 2.0 software features that help improve data integrity, traceability, and regulatory readiness.
Explore Compliance Features
Comparable Data
Maintain continuity with historical datasets and established workflows.
Support for GMP-Aligned Workflows
User controls and reporting features support regulated environments.
Flexibility Across CLD, PD, and QC
Advanced cell analysis supports CLD, PD, and QC workflows.
Reliable Performance, Familiar Hardware
Built on proven Vi-CELL BLU hardware without requiring changes to existing instrument.
Explore Vi-CELL BLU Models and Accessories
How the Vi-CELL BLU Cell Viability Analyzer works
FIRST STEP
Log in and add sample(s) to the run queue
NEXT
Review results
ALTERNATIVELY
Walk away to work on other tasks and retrieve results later
Work with Carousel or Plate
With Carousel
Remove carousel to access plate holder
With Plate
Place 96-well plate onto the plate holder
Technical Documents
FAQ on Vi-CELL BLU Cell Viability Analyzer
What are viable cells?
Viable cells are live, healthy cells in a sample. In cell viability assays, viable cells are typically assessed by indicators such as intact cell membranes, cellular function, enzymatic activity, or metabolic activity. In the context of trypan blue, viable cells are live cells with intact membranes and sufficient cellular health to support downstream culture, analysis, or processing decisions. Cell viability measurements help researchers understand the quality and health of a cell population before moving forward with experiments or bioprocessing steps.
How does trypan blue work?
Trypan blue works through a dye-exclusion principle. Viable cells have intact cell membranes that exclude the dye, so they remain unstained, while non-viable cells have compromised membranes that allow trypan blue to enter, making them appear blue. This makes trypan blue a widely used method for distinguishing live cells from dead cells during cell counting and viability analysis.
The Vi-CELL BLU Cell Viability Analyzer automates the trypan blue dye exclusion method, helping reduce manual microscopy, pipetting, and hemocytometer-based workflows.
Does the Vi-CELL BLU Cell Viability Analyzer support regulatory compliance?
Yes. The system includes data integrity and compliance features such as audit trails, electronic signatures, secure user sign-on, user-level permissions, and tools that support 21 CFR Part 11 compliance requirements.
Can the Vi-CELL BLU Cell Viability Analyzer support high-throughput workflows?
Yes. The system offers flexible sample introduction through a 24-position carousel or a 96-well plate format, making it suitable for both routine laboratory workflows and higher-throughput applications. It also supports integration with automation platforms.
Can I compare results with historical data with the Vi-CELL BLU 2.0 software?
Yes. The Vi-CELL BLU 2.0 software is designed to support a seamless transition with improved alignment to historical data, helping laboratories maintain data comparability while benefiting from enhanced accuracy and performance.
Does the Vi-CELL BLU Cell Viability Analyzer integrate with automated bioprocessing systems?
Yes. The Vi-CELL BLU Cell Viability Analyzer can be integrated with automation and bioprocessing platforms, including Sartorius Ambr® systems, Biomek automated workstations, and the Flownamics Seg-Flow S3 automated sampling system, helping streamline cell culture workflows.
